A Turning Point for Women’s Hormone Therapy: The Black Box Warning Is Gone

For decades, women were told that hormone replacement therapy was dangerous — largely due to a deeply flawed study that created fear, confusion, and misinformation around female hormones. In a long-overdue move, the FDA has now removed the black box warning on hormone therapy for women, signaling a shift back toward science.

In this episode, Dr. Greg Dennis breaks down why the warning existed in the first place, what went wrong with the original research, and why properly prescribed hormone replacement therapy is one of the most powerful tools for women’s long-term health and quality of life. We discuss the benefits of starting HRT early, why choosing the right provider matters, and the pros and cons of today’s treatment options — including pellets, creams, injections, and patches.

This is an honest, science-based conversation about why female hormone replacement therapy deserves a second look — and why it may be one of the best decisions a woman can make for her health.